Principal Investigator - Physician

Planet Group
The Villages, FL

The Role

Our client is looking to hire a dynamic, full-time Physician, Principal investigator . As a company they have taken part in the clinical trials of FDA approved therapies that slow the progression of Alzheimer’s Disease and most diagnostics (PET tracers, CSF and Blood Biomarkers) for the diagnosis of AD. Additionally, they are actively testing multiple therapeutics in the pioneering field of Alzheimer’s prevention. This is an exciting field of clinical practice with unlimited opportunities where you can practice your best medicine. The focus is on AD but as a multi-specialty research center, they also participate in clinical trials for diseases such as diabetes, CVD, OA and many others. You will work with a team of dedicated researchers including nurses and research coordinators, so please, if you are a physician who believes in teamwork and collaboration at all levels we’d be interested in speaking with you.

The typical workday involves seeing 8-10 trial patients per day, overseeing their clinical trial care and safety. Benefits include a 4-day work week, with 4 weeks PTO, and competitive salary package. The role is located in the Villages, FL, considered one of the most dynamic and active communities in the country; close to both Florida coasts and 40 miles North of Orlando. Preference given to those with prior Military Service as we value this experience and must have Neurology, Psychiatry, etc. background to be considered. A current unrestricted Florida medical license will be required. Prior Alzheimer’s Disease experience preferred but not necessary.

Primary Responsibilities of a Clinical Trial Principal Investigator

  • The PI responsibly and ethically conducts clinical trials, including providing medical oversight, maintaining integrity of the study design, and direction of the research team to ensure research is conducted in accordance with the local and national laws and regulations, including applicable FDA regulations, GCP, ICH guidelines, HIPAA, and all policies and procedures of the trial Sponsor
  • Review and discuss study protocols and obtain informed consent from patients
  • Meet with patients during designated study visits to perform assessments, including physical examinations and data collection
  • Review and interpret laboratory results, EKGs and other diagnostic and safety assessments as required per study protocol
  • Monitor safety variables, including adverse events, laboratory abnormalities, changes in patient medical status, evaluation of prescribed concomitant medications as per protocol
  • Use proper medical judgment in the interpretation and decision-making as it relates to the investigational study
  • Review, approve and ensure timely reporting of protocol deviations and Adverse Events (AE) and Serious Adverse Events (SAE)
  • Ensure accurate documentation and storage of Investigational Product
  • Ensure prompt reporting all unanticipated problems or injuries to IRB, Sponsor, or delegated representative
  • Meet with trial stakeholders as needed throughout the study
  • Review and discuss any medical or protocol-related concerns with medical monitors
  • Attend Investigator Meetings and other study-related meetings
  • Work with Sub-investigator(s), Clinical Research Coordinators, and key study personnel in overseeing the execution of study protocols
  • Other duties as assigned
Posted 2026-01-09

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