Special Project Associate II-Neuroscience-Ikezu lab for Molecular Neurotherapeutics in Alzheimer's

Mayo Clinic
Jacksonville, FL
**Why Mayo Clinic** Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans ( - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. **Benefits Highlights** + Medical: Multiple plan options. + Dental: Delta Dental or reimbursement account for flexible coverage. + Vision: Affordable plan with national network. + Pre-Tax Savings: HSA and FSAs for eligible expenses. + Retirement: Competitive retirement package to secure your future. **Responsibilities** The Molecular Neurotherapeutics Laboratory directed by Drs. Ikezu studies molecular and cellular mechanisms underlying aging and neurodegenerative disorders including Alzheimer's disease (AD) and frontotemporal dementia with a particular focus on neuroimmunology. We are interested in investigating the pathological function of small extracellular vesicles (EVs), which are known to transfer abnormal proteins as vehicles inside the brain. Our mission is to decipher the molecular machinery of EVs which could be a future therapeutic target of AD and frontotemporal dementia or aging process. The Ikezu lab is engaged in multiple arrays of cutting-edge technologies including behavioral studies, adeno-associated virus gene delivery, fluorescence activated cell sorting, proteomics, RNA sequence, super resolution confocal microscopy. The successful candidate will perform daily laboratory activities, including iPSC cell culture, animal colony maintenance, histology, EV flow cytometry, and other general laboratory inventory work. The incumbent will also assist in brain sample cryosectioning, immunohistochemistry sample processing, data collection using confocal microscope and analysis using IMARIS software. We are looking for a highly self-motivated and organized individual to join our team. The successful candidate will have a passion for science, an inquisitive mind, and a strong interest to learn and implement new knowledge. Basic laboratory, math, and computer skills as well as attention to detail are a must. Experience with animal work, molecular, cell biological and/or biochemical techniques is an advantage. We provide a supportive environment and is committed to offering individualized training, mentoring, and career development opportunities. For more details see our lab homepage: The candidate will perform daily laboratory activities, including animal colony maintenance, histology, EV flow cytometry, and other general laboratory inventory work. The incumbent will also assist in brain sample cryosectioning, immunohistochemistry sample processing, data collection using confocal microscope and analysis using IMARIS software. The position is considered non-exempt (hourly), and therefore, all hours worked must be recorded. A Special Project Associate at Mayo Clinic is a temporary position intended to execute experimental studies in support of lab goals and grant commitments as designated by the Principal Investigator. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic. The following is required for completeness of application: Current curriculum vitae with bibliography, Proof of highest degree received (if awarded a bachelor's or master's degree). Please also be prepared that you may be asked to provide two letters of recommendation to the hiring PI prior to an interview. **Qualifications** Bachelor's degree required and experience required in lab project or research work in an educational or work setting. Candidate must have a solid understanding of lab techniques, equipment, and safety. Math, and computer skills as well as attention to detail are a must. Experience with animal work, molecular, cell biological and/or biochemical techniques is an advantage. **Exemption Status** Nonexempt **Compensation Detail** $25.19 - $33.15 / hour; Education, experience and tenure may be considered along with internal equity when job offers are extended. **Benefits Eligible** Yes **Schedule** Full Time **Hours/Pay Period** 80 **Schedule Details** Varies **Weekend Schedule** Varies **International Assignment** No **Site Description** Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. ( **Equal Opportunity** All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law" ( . Mayo Clinic participates in E-Verify ( and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization. **Recruiter** Amy Hoffman **Equal opportunity** As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.
Posted 2025-11-14

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