Senior Associate Scientist I
Summary of Key Responsibilities
Hands-on lab support and process development for the chemical synthesis and downstream processing of oligonucleotide-based drug substance
Synthesis of oligonucleotides up to 11 mmol scale
Downstream processing of oligonucleotides including prep-HPLC, Ultrafiltration, annealing, concentration and Lyophilization
In process analytical testing including AX-HPLC, IPRP-HPLC, LCMS, UV-vis
Technical support for optimization of contract manufacturing processes
BS in Chemistry with 3+ years lab experience, preferably in an industrial setting.
Basic understanding of analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC-MS etc.). Related hands-on experience is preferred. Knowledge of oligonucleotide manufacture process including phosphoramidite chemistry, chromatography, ultrafiltration etc. is a plus.
Experience in record-keeping and excellent laboratory documentation practice, are required. Strong commitment to high laboratory and scientific standard; ability to maintain a safe, clean, and orderly laboratory work environment; assist in routine lab and equipment maintenance.
Good communication skills are a must for this position. The successful candidate must be a responsible and proactive individual who is able to work as a team player in a highly dynamic environment with aggressive timelines. Pay ranges between $35-44/hr based on experience
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